Line graph demonstrates the percentage of E. faecium resistant to high-level gentamicin, by survey year. Survey years include 1995, 1999, 2003, 2005, 2007, 2009 and 2010. The figure includes line graphs for invasive, non invasive, and all isolates Trend data show significant increases in high level gentamicin resistance from 1995 (15.1%) to 1999 (60.4%) and again from 2003 (46.2%) to 2010 (65.9%). The increase from 2003 to 2010 was driven by resistance in non-invasive isolates (49.4% to 74.6%) as rates of resistance remained stable in invasive isolates during that time period despite year-to-year fluctuations (41.2% to 46.0%)